Schedule for Computational Neuroscience course

MEDS 5378/BME 6110

 
Topics                             Exercises/Computer Work
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Week 1




 
 
Electrical circuits,               Install Cygwin & Genesis on PC  
Nernst equation,                   Hille Book Chap. 1
                                   GENESIS book Chap. 3
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Week 2




 
 
GENESIS book Chapter 4             GENESIS book Chapter 4 




 
 
Hodgkin-Huxley model,              Exercises 1-4




 
 
Hille Book Chap. 2
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Week 3




 
 
GENESIS book Chapter 4             GENESIS book Chapter 4




 
 
Hodgkin-Huxley model               Exercises 5-9
Hille Book Chap. 2
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Week 4




 
 
GENESIS book Chapter 6             GENESIS book Chapter 6
Temporal interactions of PSPs      Exercises 1-5
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Week 5




 
 
Cable theory, passive dendrites    GENESIS book Chapter 5
                                   Exercises 1-3
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Week 6




 
 
Cable theory                       GENESIS book Chapter 5 




 
 
passive & active dendrites         Exercises 4-7




 
 
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Week 7




 
 
Model of DCN fusiform cell         Demonstration of the cell model
Kim et al.,1994,JASA 96:1501)      A-type potassium channel  
Hille book Chap. 5
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Week 8




 
 
Present. of students'              Present. of students'
simulation proposals               simulation proposals
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Deadline for submission of the written proposal of the simulation
project. It should include a title, hypothesis, specific aims and
a brief description of the planned simulation;
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Week 9




 
 
GENESIS Chap. 7                    GENESIS Chapter 7
Ion channels in bursting neurons   Exercises




 
 
Hille book Chap. 5
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Week 10




 
 
GENESIS Chap. 8                    GENESIS Chapter 8




 
 
Central pattern generator          Exercises




 
 
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Week 11
Hille book Chap. 8 
Ion channels for sensory transduction




 
 
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Week 12




 
 
GENESIS Chap. 12-18                GENESIS Chapters 12-18
GENESIS methods                    Exercises
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Week 13




 
 
Thanksgiving recess




 
 
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Week 14




 
 
Prelim. Presentations of Proj. Prelim. Presentations of Proj.
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Week 15




 
 
Prelim. Presentations of Proj. Prelim. Presentations of Proj.
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Week 16
Final presentations and submission of the written 




 
 
report of the simulation project;                 
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Note: The grade of the course will be based on the simulation
project (75%) and class participation including computer
exercises (25%).
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